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Merck Serono: Study Published In JCO Shows Erbitux Enhances Efficacy In MCRC Patients With KRAS Wild-Type Tumors In 1st-Line Setting - A study published today in the Journal of Clinical Oncology demonstrates that the addition of Erbitux® (cetuximab) to standard oxaliplatin-based chemotherapy (FOLFOX-4) in previously untreated metastatic colorectal cancer (mCRC) patients with KRAS wild-type tumors results in significantly higher efficacy than chemotherapy alone....
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Immutep Announces Positive Interim Results In Phase I/II Chemoimmunotherapy Trial In Breast Cancer - Immutep S.A. announced today interim results from its ongoing Phase I/II chemoimmunotherapy clinical trial in metastatic breast carcinoma. ImmuFact IMP321 was administered the day after weekly paclitaxel for six months. The interim results show a clinical response rate of 50 per cent compared to 25 per cent with paclitaxel alone....
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Study Links Obesity To Elevated Risk Of Ovarian Cancer - A new epidemiological study has found that among women who have never used menopausal hormone therapy, obese women are at an increased risk of developing ovarian cancer compared with women of normal weight....
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FDA Announces Class I Recall Of Ophthalmic Surgical Device - The U.S. Food and Drug Administration announced a Class I recall of lot no. UD30654 of Healon D, an ophthalmic viscosurgical device (OVD) manufactured by Advanced Medical Optics Inc. (AMO) of Santa Ana, Calif. OVDs are viscoelastic materials used to maintain space in the eye during surgery. Typically, OVDs are pre-packaged in a syringe and are applied using a small tube. On Oct....
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FDA Prevents Two Dairies From Adulterating Animal Drugs And Food - The U.S. Food and Drug Administration announced today that the District Court for the District of New Mexico has enjoined Do-Rene and Clover Knolls Dairies and their owners, Douglas B. Handley and Irene Handley, from adulterating new animal drugs and introducing adulterated food into commerce. Both companies are based in Clovis, N.M....
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Getting A Good Deal On Gym Membership - New Year is the time when many people decide to join a gym, or revisit a neglected gym membership, and in the current economic climate, gym owners will be concerned not only to attract new members but also to hold onto their existing ones, so now is a good time to get a good deal on your gym membership....
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Building Work Starts On The Largest IVF Facility In The NHS, UK - A £3.3m plan to reorganise Reproductive Medicine services in Leeds, bringing them together for the first time in a single purpose-designed facility which will improve care for fertility patients, is getting underway....
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What If The Treatment Doesn't Work: Nailing Steroid Resistant Asthma - Nailing steroid resistant asthma was the focus of a recent Biomedical Forum for clinicians, researchers and allied health professionals from Guy's and St Thomas' and King's College Hospital NHS Foundation Trusts and King's College London....
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American Medical Student Association Applauds Pharmaceutical Industry For Voluntary Ban; Continues To Call For Federal Regulation - The American Medical Student Association (AMSA), the nation's oldest and largest, independent association for physicians-in-training, applauds the pharmaceutical industry for implementing a voluntary ban on gifts to physicians, which began on January 1, 2009....
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MHRA - Brief Summary Of Reclassifications That Have Been Approved In The Past 12 Months, UK - Please see the relevant entry in List C (consolidated list of substances present in authorised products which have been reclassified since 1 April 2002) for full details....
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MRSA At Record Low For The Chesterfield Royal Hospital, England - The Chesterfield Royal Hospital has recorded its lowest yearly MRSA rates since records began. The latest statistics have been released by the Health Protection Agency with just ten cases recorded at the Royal in the year between April 2007 and March 2008. And the news gets better with the hospital on course to do even better this year with only five recorded cases since April 1st....
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Hospitals Consult On Proposal To Become An NHS Foundation Trust - Lincolnshire, England - Communities across Lincolnshire are being invited to get involved and have their say on the next step for the future of the county's hospitals, by attending a consultation event in their area. The United Lincolnshire Hospitals NHS Trust intends to apply for NHS Foundation Trust status....
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New Device Couples, Fuses Cells For Stem Cell Research - MIT engineers have developed a new, highly efficient way to pair up cells so they can be fused together into a hybrid cell. The new technique should make it much easier for scientists to study what happens when two cells are combined. For example, fusing an adult cell and an embryonic stem cell allows researchers to study the genetic reprogramming that occurs in such hybrids....
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Novel Glioblastoma Mouse Model Developed By Salk Researchers - Researchers at the Salk Institute for Biological Studies have developed a versatile mouse model of glioblastoma - the most common and deadly brain cancer in humans - that closely resembles the development and progression of human brain tumors that arise naturally. "Mouse models of human cancer have taught us a great deal about the basic principles of cancer biology," says Inder Verma, Ph.D....
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Discovery Could Improve Understanding Of Ulcerative Colitis, Lead To New Therapies - An international team led by University of Pittsburgh School of Medicine researchers has identified genetic markers associated with risk for ulcerative colitis....
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The High Societal, Economic Burden Of Insomnia Shown By Study - A study in the Jan. 1 issue of the journal Sleep indicates that the indirect costs of untreated insomnia are significantly greater than the direct costs associated with its treatment. The study estimates that the total annual cost of insomnia in the province of Quebec is 6.5 billion Canadian dollars, representing about one percent of the province's $228....
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Factors Other Than Central Sleep Apnea May Contribute To Poor Sleep Quality In Heart-Failure Patients - A study in the Jan. 1 issue of the journal Sleep demonstrates that the frequent arousals from sleep that occur in heart failure patients with central sleep apnea (CSA) may reflect the presence of another underlying arousal disorder rather than being a defensive mechanism to terminate apneas....
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Reducing Otolaryngic Surgical Infection Rates By Pre-Screening For MRSA - Pre-operative screening of patients for methicillin-resistant staphylococcus aureus (MRSA) may be an effective way to reduce infection rates following otolaryngic surgeries, according to new research published in the January 2009 issue of Otolaryngology - Head and Neck Surgery....
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Toxicity Mechanism Identified For Parkinson's Disease - Neurologists have observed for decades that Lewy bodies, clumps of aggregated proteins inside cells, appear in the brains of patients with Parkinson's disease and other neurodegenerative diseases....
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Antioxidants Offer Pain Relief In Patients With Chronic Pancreatitis - Antioxidant supplementation was found to be effective in relieving pain and reducing levels of oxidative stress in patients with chronic pancreatitis (CP), reports a new study in Gastroenterology. CP is a progressive inflammatory disease of the pancreas in which patients experience abdominal pain (in early stage) and diabetes and maldigestion (in late stage)....
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DNA Nanotubes May Soon Find Their Way Into A New Generation Of Ultra-Tiny Electronic And Biomedical Innovations - Arizona State University researchers Hao Yan and Yan Liu imagine and assemble intricate structures on a scale almost unfathomably small. Their medium is the double-helical DNA molecule, a versatile building material offering near limitless construction potential....
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Earlier, Individualized Treatment Of Thyroid Cancer Enabled By Molecular Imaging - In a study to determine the diagnostic value of molecular imaging in nodal staging of patients with thyroid cancer, researchers were able for the first time to accurately distinguish between cancerous cells in regional lymph nodes and normal residual thyroid tissue directly after surgery....
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New Congenital Neutropenia Syndrome And Causative Gene Mutation Identified By Scientists - A team of scientists has discovered a new syndrome associated with severe congenital neutropenia (SCN), a rare disorder in which children lack sufficient infection-fighting white cells, and identified the genetic cause of the syndrome: mutations in the gene Glucose-6-phosphatase, catalytic subunit 3 (G6PC3). The findings, which are published in the Jan....
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Transplant Program At UT Southwestern University Hospital Recognized For Increasing Organ Donor Rates - The surgical transplant team at UT Southwestern University Hospital has garnered twin awards for its successful efforts to increase organ donation rates. "Each organ donation is an opportunity for new life, so we are gratified with these recognitions," said Dr. Juan Arenas, chief of surgical transplantation and surgical director for the liver transplant program....
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Pharmaceutical Companies Seek Clarity On Evidence Needed For Drug Label Change - With the discovery of a growing number of predictive biomarkers for existing drugs, the question of when and how to add pharmacogenetic information to drug labels has taken on greater urgency. On December 16 the Oncologic Drug Advisory Committee (ODAC) of the Food and Drug Administration (FDA) met in Gaithersburg, MD with representatives from pharmaceutical companies Amgen and Imclone....
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Resolve To Make Folic Acid A Daily Habit This Year - Tennessee Department Of Health - The Department of Health is reminding all women of childbearing age about the need for folic acid, whether they're planning a baby right now or not. The Department will join observances of Folic Acid Awareness Week January 5 - 11, 2009....
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Pennsylvania Department Of Health Encourages Smokers To Put Quitting At Top Of Resolution List - Department of Health Acting Secretary Everette James today urged Pennsylvania smokers to make quitting smoking their top New Year's resolution for 2009. "The start of a new year presents an opportunity to make positive changes in our lives," said James. "While quitting smoking is rarely easy, having a plan and seeking support can greatly increase your chances of succeeding....
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Debunking The Detox Myth - A group of over 300 young UK scientists and engineers who investigated the evidence behind claims made for products and diets, have started a public awareness campaign by publishing a dossier that shows the word "detox" has no meaning outside of the clinical treatment of drug addiction and poisoning....
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Osteoporosis Drug Linked To Bone Death In Jaw - A new US study found that even short term use of oral bisphosphonates like Fosomax (alendronate), commonly used to treat osteoporosis, may leave the jaw vulnerable to devastating necrosis (death of bone tissue)....
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Cold Weather Brings Hypothermia Threat - Oregon Department Of Health - Low winter temperatures have brought warnings from experts in the Oregon Department of Human Services State Public Health Division. Exposure to cold can lead to hypothermia, so it is important to protect yourself against it. Hypothermia occurs when heat escapes from your body faster than it can warm itself and you body's core body temperature falls lower than 95 degrees F....
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Department Of Health Surveys New Mexicans To Improve Their Health - Starting at the beginning of January, the New Mexico Department of Health will call New Mexicans to survey them about their health behaviors for the Department's annual survey, Behavioral Risk Factor Surveillance System. The survey is designed to provide information on behaviors and risk factors for chronic and infectious diseases and other health conditions among adults in New Mexico....
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It's A GO! New Jersey State Combines Medicaid Waivers For Seniors & Adults With Physical Disabilities - Department of Health and Senior Services (DHSS) Commissioner Heather Howard announced today the State has received approval from the U.S. Centers for Medicare and Medicaid Services to consolidate three Medicaid-supported home and community-based service programs currently operated by DHSS into a single program known as Global Options (GO) for Long Term Care....
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Physicians Key In Helping People Quit Smoking - But Most People Don't Ask Their Physician - Montana physicians play a key role in helping people quit using tobacco products. However, a Montana Tobacco Use Prevention Program (MTUPP) survey shows most people don't often ask their physician to help them quit smoking. Consequently, MTUPP sent 2,500 letters to Montana physicians urging them to take the initiative with their patients....
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Popular New Year's Resolutions Also Promote Urologic/Sexual Health - Already having a hard time sticking to your New Year's resolutions? The American Urological Association (AUA) can provide some much-needed motivation: many popular New Year's resolutions can actually improve your urologic or sexual health....
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Dentist Links Fosomax-type Drugs To Jaw Necrosis - Researchers at the University Of Southern California, School Of Dentistry release results of clinical data that links oral bisphosphonates to increased jaw necrosis....
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Expectant Brains Help Predict Anxiety Treatment Success - A network of emotion-regulating brain regions implicated in the pathological worry that can grip patients with anxiety disorders may also be useful for predicting the benefits of treatment. A new study appearing online Jan. 2 reports that high levels of brain activity in an emotional center called the amygdala reflect patients' hypersensitivity to anticipation of adverse events....
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Trying To Eat Less Becomes More Important To Fend Off Middle Age Weight Gain - Lots of experts disagree over the seemingly obvious notion of keeping weight off by trying to eat less a debate that centers on whether the practice backfires, leading to binging and weight gain. Now a new study shows that practicing restraint becomes more important with age....
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Family History Of Prostate Cancer Does Not Affect Some Treatment Outcomes - In a first of its kind study, a first-degree family history of prostate cancer has no impact on the treatment outcomes of prostate cancer patients treated with brachytherapy (also called seed implants), and patients with this type of family history have clinical and pathologic characteristics similar...
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Dormant Cancer Cells Rely On Cellular Self Cannibalization To Survive - A single tumor-suppressing gene is a key to understanding, and perhaps killing, dormant ovarian cancer cells that persist after initial treatment only to reawaken years later, researchers at The University of Texas M. D. Anderson Cancer Center report in the December Journal of Clinical Investigation....
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Department Of Health Recognizes January As Cervical Health Awareness Month - As a part of National Cervical Health Awareness Month, Acting Secretary of Health Everette James today reminded women of the importance of cervical cancer prevention and the need for pap tests. "Every January as we begin a new year, we want to remind all Pennsylvanians to do what they can to improve their overall health," said James....
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Parkinson's Disease Plays Havoc With Common Orthopaedic Conditions - Although Parkinson's disease (PD) is a neurological disorder, according to an article in the January 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons, the disease also increases a person's risk of experiencing complicated orthopaedic conditions....
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Replacing Your Total Hip Replacement - Each year thousands of patients undergo total hip replacement surgery in order to help alleviate pain associated with debilitating hip disease and other related hip problems. According to a new study published in the January 2009 issue of The Journal of Bone and Joint Surgery (http://www.ejbjs....
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MRI Emerges As Vital Resource In Treatment Of Back Pain - Magnetic resonance imaging (MRI) is a growing technology providing an increasing number of clinical benefits when used in the evaluation of back pain according to an article in the January 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons (http://www.jaaos.org)....
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Bionovo Publishes Discoveries In Predictable Tissue Selectivity For Selective Estrogen Receptor Modulators Platform - Bionovo, Inc. (Nasdaq: BNVI) announced results describing predictable estrogen regulatory elements that can be used to identify estrogenic drugs that are safer....
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Resolutions For Healthy Families In A Healthy Montana - By Eat Right Montana - Since January 1999, Eat Right Montana (ERM), a statewide coalition promoting healthy eating and active lifestyles, has published a monthly packet of sound advice on nutrition and fitness. For its 11th year, the coalition plans to expand and enhance the practical tips it offers to Montanans with the 2009 theme - Going Green: Simple Steps for Healthy Families....
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Smoking Cessation Program For Veterans Off To Big Start - Commonwealth Of Massachusetts - One month after the Department of Veterans' Services (DVS) and the Department of Public Health (DPH) launched a joint veterans' smoking cessation program at the State House, the quit line has received over 500 calls. On average, the quit line received 15-20 calls each day....
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January Is Cervical Cancer Awareness Month - Commonwealth Of Kentucky - More women in Kentucky should join the fight to end cervical cancer by getting vaccinated and undergoing regular screenings for the disease, the Kentucky Department for Public Health (DPH) announced today. Women age 9 to 26 years old can receive a vaccine to prevent the human papillomavirus (HPV) linked to cervical cancer....
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Diseases To Watch For In 2009 Include Hantavirus - The Iowa Dept. of Public Health (IDPH) urges Iowans to take steps to stay healthy in 2009. Influenza season is entering its most active months; in addition, recent cases of norovirus, shigellosis and hantavirus offer opportunities to remind Iowans that good hygiene and disease prevention are the best ways to avoid illness. The best prevention against influenza is receiving a yearly flu shot....
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FDA Approves Most Comprehensive System To Test Donated Blood For HIV, Hepatitis B & Hepatitis C - The United States Food & Drug Administration (FDA) approved a new nucleic acid test from Roche to screen donated blood for HIV-1 Group M RNA, hepatitis C RNA and hepatitis B DNA in a single, automated assay....
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Hawai'i DOH Launches Enhanced Online Licensing For Clinical Laboratory Professionals - Renewing Hawai'i state clinical laboratory personnel licenses just got easier. The Hawai'i State Department of Health (DOH) State Laboratories Division (SLD) now allows clinical laboratory professionals to update their profiles and pay license renewal fees online....
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Keep Your New Year's Resolution To Lose Weight - With the sumptuous food and treats available during the holiday season, it's easy for us overdo it - even while we are adopting a New Year's resolution to lose weight and be active. "Making a resolution to lose weight today is an important first step to a long and healthy life," said Department of Health Services Secretary Karen Timberlake....
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Central United States Earthquake Consortium And CDC To Host Post-Earthquake Public Health And Medical Issues Course In Arkansas - On February 4, 2009, the Central United States Earthquake Consortium (CUSEC), in cooperation with the Centers for Disease Control and Prevention (CDC), is presenting a one-day class titled "Disaster Medicine 101: Post-Earthquake Public Health and Medical Issues in the New Madrid Seismic Zone" at the Arkansas Department of Health (ADH) Auditorium. The class will begin at 8:30 a.m....
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ADHS Stresses Importance Of Folic Acid For Young Women - "An ounce of prevention is worth a pound of cure." That old adage is quite true when it comes to reducing brain and spinal birth defects. Today, the Arizona Department of Health Services launched an awareness campaign to stress the importance of preventing those birth defects by taking a multivitamin. In Arizona, more than 50 babies are born with brain and spine birth defects each year....
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Texas DSHS To Resume Annual Wintertime Rabies Bait Drop Jan. 7 - The Texas Department of State Health Services' annual airdrop of vaccine baits, credited with turning the tide against the spread of rabies strains carried by coyotes and gray foxes, will begin next week. Some 2.9 million baits will be dropped over parts of 41 Texas counties....
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Nebraska DHHS Offers Low-Cost Radon Test Kits - January Is Radon Action Month - To make it easier for Nebraskans to test their homes for radon, the Radon Program of the Nebraska Department of Health and Human Services is offering low-cost radon test kits. Governor Dave Heineman has proclaimed January to be Radon Action Month. January is an opportune time for Nebraskans to test for radon in their homes, according to Dr. Joann Schaefer, the state's Chief Medical Officer....
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Alzheimer's Society Comment On Research Suggesting That Sleep Disorder May Be An Early Sign Of Dementia Or Parkinson's Disease - People who act out their dreams through kicking and crying out in their sleep may go on to develop dementia or Parkinson's disease, according to a study published in the online issue of Neurology. In the research 93 people with REM sleep behaviour disorder who had no signs of a neurodegenerative disease were followed for an average of five years....
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Using Gold Particles To Release Multiple Drugs In A Controlled Fashion - Nanoparticles Could Treat Cancer And Other Diseases - Using tiny gold particles and infrared light, MIT researchers have developed a drug-delivery system that allows multiple drugs to be released in a controlled fashion. Such a system could one day be used to provide more control when battling diseases commonly treated with more than one drug, according to the researchers....
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Study Links Molecule To Muscle Maturation, Muscle Cancer - Researchers at The Ohio State University Comprehensive Cancer Center have discovered that a molecule implicated in leukemia and lung cancer is also important in muscle repair and in a muscle cancer that strikes mainly children....
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Writing Chemotherapy Orders On The Day Of Administration And Improved Communication Could Reduce Medication Errors - Seven percent of adults and 19 percent of children taking chemotherapy drugs in outpatient clinics or at home were given the wrong dose or experienced other mistakes involving their medications, according to a new study led by Kathleen E....
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Johns Hopkins Scientists Pull Protein's Tail To Curtail Cancer - When researchers look inside human cancer cells for the whereabouts of an important tumor-suppressor, they often catch the protein playing hooky, lolling around in cellular broth instead of muscling its way out to the cells' membranes and foiling cancer growth....
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